diff --git a/.github/workflows/multi_arch_ci_linux.yml b/.github/workflows/multi_arch_ci_linux.yml
index 5415cf36c7c..5f0d62b16f9 100644
--- a/.github/workflows/multi_arch_ci_linux.yml
+++ b/.github/workflows/multi_arch_ci_linux.yml
@@ -287,22 +287,48 @@ jobs:
   # so the split path is unconditional here. The split itself runs inline
   # in multi_arch_build_portable_linux_pytorch_wheels_ci.yml based on
   # inputs.kpack_split.
+  #
+  # Per-ref amdgpu family exclusions (e.g. gfx125x on release/2.10) are
+  # applied via configure_pytorch_release_matrix.py, matching the release
+  # workflow in multi_arch_release_linux_pytorch_wheels.yml.
+  setup_pytorch_matrix:
+    name: Setup PyTorch CI Matrix
+    if: ${{ fromJSON(inputs.build_config).build_pytorch == true }}
+    runs-on: ubuntu-24.04
+    outputs:
+      pytorch_matrix: ${{ steps.matrix.outputs.pytorch_matrix }}
+    steps:
+      - name: Checkout
+        uses: actions/checkout@df4cb1c069e1874edd31b4311f1884172cec0e10 # v6.0.3
+        with:
+          repository: ${{ inputs.repository || github.repository }}
+          ref: ${{ inputs.ref }}
+
+      - name: Generate PyTorch matrix
+        id: matrix
+        run: |
+          python ./build_tools/github_actions/configure_pytorch_release_matrix.py \
+            --python-versions="3.12" \
+            --platform=linux \
+            --pytorch-refs="release/2.10;release/2.11;release/2.12" \
+            --amdgpu-families="${{ fromJSON(inputs.build_config).dist_amdgpu_families }}"
+
   build_pytorch_wheel_fat:
-    needs: [build_python_packages]
+    needs: [build_python_packages, setup_pytorch_matrix]
     name: Build PyTorch (fat + split) | ${{ matrix.pytorch_git_ref }}
     if: ${{ !failure() && !cancelled() && fromJSON(inputs.build_config).build_pytorch == true }}
     strategy:
       fail-fast: false
       matrix:
-        pytorch_git_ref: ["release/2.10", "release/2.11", "release/2.12"]
+        include: ${{ fromJSON(needs.setup_pytorch_matrix.outputs.pytorch_matrix) }}
     uses: ./.github/workflows/multi_arch_build_portable_linux_pytorch_wheels_ci.yml
     with:
       artifact_group: ${{ fromJSON(inputs.build_config).artifact_group }}
-      python_version: "3.12"
+      python_version: ${{ matrix.python_version }}
       pytorch_git_ref: ${{ matrix.pytorch_git_ref }}
-      # The reusable workflow expands this to gfx targets via
-      # cmake/therock_amdgpu_targets.cmake.
-      amdgpu_families: ${{ fromJSON(inputs.build_config).dist_amdgpu_families }}
+      # Per-ref families from configure_pytorch_release_matrix.py; expanded
+      # to gfx targets via cmake/therock_amdgpu_targets.cmake.
+      amdgpu_families: ${{ matrix.amdgpu_families }}
       kpack_split: ${{ needs.build_python_packages.outputs.kpack_split }}
       rocm_package_find_links_url: ${{ needs.build_python_packages.outputs.package_find_links_url }}
       rocm_version: ${{ inputs.rocm_package_version }}
diff --git a/build_tools/github_actions/configure_pytorch_release_matrix.py b/build_tools/github_actions/configure_pytorch_release_matrix.py
index 69c68e0e506..716706eae37 100644
--- a/build_tools/github_actions/configure_pytorch_release_matrix.py
+++ b/build_tools/github_actions/configure_pytorch_release_matrix.py
@@ -40,9 +40,7 @@
     },
     {
         "pytorch_git_ref": "release/2.11",
-        # gfx125x not yet upstreamed to pytorch/pytorch.
-        # See https://github.com/ROCm/TheRock/issues/5833.
-        "exclude_amdgpu_families": {"gfx125x"},
+        # gfx125x upstreamed via https://github.com/ROCm/pytorch/pull/3346.
     },
     {
         "pytorch_git_ref": "release/2.12",
@@ -94,12 +92,16 @@ def generate_pytorch_matrix(
     python_versions: list[str] | None,
     amdgpu_families: str,
     platform: str = "linux",
+    pytorch_refs: list[str] | None = None,
 ) -> list[dict]:
     versions = python_versions if python_versions else PYTHON_VERSIONS
-    pytorch_refs = PYTORCH_REFS_WINDOWS if platform == "windows" else PYTORCH_REFS_LINUX
+    refs_cfg = PYTORCH_REFS_WINDOWS if platform == "windows" else PYTORCH_REFS_LINUX
+    if pytorch_refs is not None:
+        ref_set = {r.strip() for r in pytorch_refs if r.strip()}
+        refs_cfg = [cfg for cfg in refs_cfg if cfg["pytorch_git_ref"] in ref_set]
     matrix = []
     for py in versions:
-        for ref_cfg in pytorch_refs:
+        for ref_cfg in refs_cfg:
             ref = ref_cfg["pytorch_git_ref"]
             exclude = ref_cfg.get("exclude_amdgpu_families", set())
             families = _filter_families(amdgpu_families, exclude)
@@ -139,6 +141,15 @@ def main(argv: list[str] | None = None) -> int:
             "filtered out of this list for that ref's matrix entry."
         ),
     )
+    parser.add_argument(
+        "--pytorch-refs",
+        type=str,
+        default="",
+        help=(
+            "Comma or semicolon separated list of PyTorch git refs to include "
+            "(default: all configured refs for the platform)"
+        ),
+    )
     args = parser.parse_args(argv)
 
     python_versions = None
@@ -148,8 +159,16 @@ def main(argv: list[str] | None = None) -> int:
             v.strip() for v in args.python_versions.split(sep) if v.strip()
         ]
 
+    pytorch_refs = None
+    if args.pytorch_refs:
+        sep = ";" if ";" in args.pytorch_refs else ","
+        pytorch_refs = [r.strip() for r in args.pytorch_refs.split(sep) if r.strip()]
+
     matrix = generate_pytorch_matrix(
-        python_versions, args.amdgpu_families, args.platform
+        python_versions,
+        args.amdgpu_families,
+        args.platform,
+        pytorch_refs,
     )
     gha_set_output({"pytorch_matrix": json.dumps(matrix)})
     return 0
diff --git a/build_tools/github_actions/tests/configure_pytorch_release_matrix_test.py b/build_tools/github_actions/tests/configure_pytorch_release_matrix_test.py
new file mode 100644
index 00000000000..4be2b9dfea5
--- /dev/null
+++ b/build_tools/github_actions/tests/configure_pytorch_release_matrix_test.py
@@ -0,0 +1,49 @@
+# Copyright Advanced Micro Devices, Inc.
+# SPDX-License-Identifier: MIT
+
+import os
+import sys
+import unittest
+from pathlib import Path
+
+THIS_DIR = Path(__file__).resolve().parent
+sys.path.insert(0, os.fspath(THIS_DIR.parent))
+
+import configure_pytorch_release_matrix as m
+
+
+class ConfigurePyTorchReleaseMatrixTest(unittest.TestCase):
+    def test_release_2_10_excludes_gfx125x(self) -> None:
+        matrix = m.generate_pytorch_matrix(
+            python_versions=["3.12"],
+            amdgpu_families="gfx94X-dcgpu;gfx125X-dcgpu",
+            platform="linux",
+            pytorch_refs=["release/2.10"],
+        )
+        self.assertEqual(len(matrix), 1)
+        self.assertEqual(matrix[0]["pytorch_git_ref"], "release/2.10")
+        self.assertEqual(matrix[0]["amdgpu_families"], "gfx94X-dcgpu")
+
+    def test_release_2_11_includes_gfx125x(self) -> None:
+        matrix = m.generate_pytorch_matrix(
+            python_versions=["3.12"],
+            amdgpu_families="gfx94X-dcgpu;gfx125X-dcgpu",
+            platform="linux",
+            pytorch_refs=["release/2.11"],
+        )
+        self.assertEqual(len(matrix), 1)
+        self.assertEqual(matrix[0]["amdgpu_families"], "gfx94X-dcgpu;gfx125X-dcgpu")
+
+    def test_pytorch_refs_filter_limits_matrix_rows(self) -> None:
+        matrix = m.generate_pytorch_matrix(
+            python_versions=["3.12"],
+            amdgpu_families="gfx94X-dcgpu",
+            platform="linux",
+            pytorch_refs=["release/2.10", "release/2.11"],
+        )
+        refs = {row["pytorch_git_ref"] for row in matrix}
+        self.assertEqual(refs, {"release/2.10", "release/2.11"})
+
+
+if __name__ == "__main__":
+    unittest.main()