diff --git a/public/msk_spectrum_tme_2022/meta_absolute_counts.txt b/public/msk_spectrum_tme_2022/meta_absolute_counts.txt
index ac49f8708d..00aaa17fe4 100644
--- a/public/msk_spectrum_tme_2022/meta_absolute_counts.txt
+++ b/public/msk_spectrum_tme_2022/meta_absolute_counts.txt
@@ -4,7 +4,7 @@ generic_assay_type: SINGLE_CELL_ABSOLUTE_CELL_TYPE_COUNTS
 datatype: LIMIT-VALUE
 stable_id: cell_type_absolute_counts
 profile_name: Cell Type Absolute Counts
-profile_description: Cell Type Absolute Counts
+profile_description: Cell Type Absolute Counts. Caveat: Counts are derived from CD45 FACS-sorted scRNA-seq, so each sample's composition reflects its sort gate (some samples are immune-only or non-immune-only) rather than whole-tumor cellularity.
 data_filename: data_absolute_counts.txt
 show_profile_in_analysis_tab: true
 pivot_threshold_value: 0.000001
diff --git a/public/msk_spectrum_tme_2022/meta_cell_gating.txt b/public/msk_spectrum_tme_2022/meta_cell_gating.txt
new file mode 100644
index 0000000000..d4ba5d4c44
--- /dev/null
+++ b/public/msk_spectrum_tme_2022/meta_cell_gating.txt
@@ -0,0 +1,10 @@
+cancer_study_identifier: msk_spectrum_tme_2022
+genetic_alteration_type: GENERIC_ASSAY
+generic_assay_type: SINGLE_CELL_GATING
+datatype: CATEGORICAL
+stable_id: cell_gating
+profile_name: scRNA Cell Gating
+profile_description: CD45 flow-sort gate(s) sequenced by scRNA-seq for each sample's tumor site (Vazquez-Garcia et al. 2022, Suppl. Table 2). Indicates which compartment(s) the cell-type fraction tracks represent; samples from a single gate show a one-sided (immune-only or non-immune-only) composition rather than whole-tumor cellularity.
+data_filename: data_cell_gating.txt
+show_profile_in_analysis_tab: true
+generic_entity_meta_properties: NAME,DESCRIPTION,URL
\ No newline at end of file
diff --git a/public/msk_spectrum_tme_2022/meta_relative_fraction.txt b/public/msk_spectrum_tme_2022/meta_relative_fraction.txt
index fe2392e208..d273ef5779 100644
--- a/public/msk_spectrum_tme_2022/meta_relative_fraction.txt
+++ b/public/msk_spectrum_tme_2022/meta_relative_fraction.txt
@@ -4,7 +4,7 @@ generic_assay_type: SINGLE_CELL_RELATIVE_CELL_TYPE_COUNTS
 datatype: LIMIT-VALUE
 stable_id: cell_type_relative_counts
 profile_name: Cell Type Relative Fractions
-profile_description: Cell Type Relative Fractions.
+profile_description: Cell Type Relative Fractions. Caveat: Fractions are derived from CD45 FACS-sorted scRNA-seq, so each sample's composition reflects its sort gate (some samples are immune-only or non-immune-only) rather than whole-tumor cellularity.
 data_filename: data_relative_fraction.txt
 show_profile_in_analysis_tab: true
 pivot_threshold_value: 0.000001