diff --git a/pyproject.toml b/pyproject.toml
index 0efe9ba..0dd1735 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -46,7 +46,7 @@ ovito = { version = "*", optional = true }
 plotly = { version = "6.0.1", optional = true }
 dash = { version = "3.0.4", optional = true }
 pyyaml = { version = "6.0.2", optional = true }
-rdkit = { version = "2024.9.6", optional = true }
+rdkit = { version = "2025.3.3", optional = true }
 
 [tool.poetry.group.dev.dependencies]
 pytest = "8.3.5"