diff --git a/data/containers/patches.yaml b/data/containers/patches.yaml
index 159aa99b1691..6e70f0983d7c 100644
--- a/data/containers/patches.yaml
+++ b/data/containers/patches.yaml
@@ -69,6 +69,7 @@ docker-py:
   # https://github.com/docker/docker-py/pull/3373 - test_create_with_ipv6_address: enable IPv6
   # https://github.com/docker/docker-py/pull/3380 - integration: Remove test_build_squash tests
   # https://github.com/docker/docker-py/pull/3393 - tests: Make stream assertions robust to chunk splitting
+  # https://github.com/docker/docker-py/pull/3407 - Fix integration tests on non-amd64 hosts
   3261:
   3290:
   3354:
@@ -79,6 +80,7 @@ docker-py:
   3373:
   3380:
   3393:
+  3407:
 
 moby:
   # https://github.com/moby/moby/pull/51219 - integration/container: Make tests runnable on SELinux enabled daemon
diff --git a/data/containers/patches/docker-py/3407.patch b/data/containers/patches/docker-py/3407.patch
new file mode 100644
index 000000000000..9dd76bbbe488
--- /dev/null
+++ b/data/containers/patches/docker-py/3407.patch
@@ -0,0 +1,94 @@
+From 9e9f8ff315fe405d7f7e89b394d6269217c51dfe Mon Sep 17 00:00:00 2001
+From: =?UTF-8?q?Pawe=C5=82=20Gronowski?= <pawel.gronowski@docker.com>
+Date: Tue, 2 Jun 2026 19:56:25 +0200
+Subject: [PATCH 1/2] Skip tests incompatible with host architecture
+MIME-Version: 1.0
+Content-Type: text/plain; charset=UTF-8
+Content-Transfer-Encoding: 8bit
+
+Don't run tests that run native amd64 binaries on hosts with other
+architectures.
+
+Signed-off-by: Paweł Gronowski <pawel.gronowski@docker.com>
+---
+ tests/integration/api_plugin_test.py        | 5 +++++
+ tests/integration/credentials/store_test.py | 5 +++++
+ 2 files changed, 10 insertions(+)
+
+diff --git a/tests/integration/api_plugin_test.py b/tests/integration/api_plugin_test.py
+index 168c81b231..cc5c8d3d2e 100644
+--- a/tests/integration/api_plugin_test.py
++++ b/tests/integration/api_plugin_test.py
+@@ -1,4 +1,5 @@
+ import os
++import platform
+ 
+ import pytest
+ 
+@@ -11,6 +12,10 @@
+ 
+ 
+ @requires_api_version('1.25')
++@pytest.mark.skipif(
++    platform.machine().lower() not in ('amd64', 'x86_64'),
++    reason='vieux/sshfs plugin is only supported on amd64',
++)
+ class PluginTest(BaseAPIIntegrationTest):
+     @classmethod
+     def teardown_class(cls):
+diff --git a/tests/integration/credentials/store_test.py b/tests/integration/credentials/store_test.py
+index e1eba33a18..a9cb51469c 100644
+--- a/tests/integration/credentials/store_test.py
++++ b/tests/integration/credentials/store_test.py
+@@ -1,4 +1,5 @@
+ import os
++import platform
+ import random
+ import shutil
+ import sys
+@@ -14,6 +15,10 @@
+ )
+ 
+ 
++@pytest.mark.skipif(
++    platform.machine().lower() not in ('amd64', 'x86_64'),
++    reason='docker-credential-pass test helper is only supported on amd64',
++)
+ class TestStore:
+     def teardown_method(self):
+         for server in self.tmp_keys:
+
+From 9b4b9b8461966e5b54638490e66c91e45f25ea19 Mon Sep 17 00:00:00 2001
+From: =?UTF-8?q?Pawe=C5=82=20Gronowski?= <pawel.gronowski@docker.com>
+Date: Tue, 2 Jun 2026 20:08:45 +0200
+Subject: [PATCH 2/2] gha: Add arm64 integration CI
+MIME-Version: 1.0
+Content-Type: text/plain; charset=UTF-8
+Content-Transfer-Encoding: 8bit
+
+Signed-off-by: Paweł Gronowski <pawel.gronowski@docker.com>
+---
+ .github/workflows/ci.yml | 13 +++++++++++++
+ 1 file changed, 13 insertions(+)
+
+diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
+index 50727826b7..dac54e8c25 100644
+--- a/.github/workflows/ci.yml
++++ b/.github/workflows/ci.yml
+@@ -70,3 +70,16 @@ jobs:
+                   docker logout
+                   rm -rf ~/.docker
+                   make ${{ matrix.variant }}
++
++    arm64-integration-tests:
++        runs-on: ubuntu-24.04-arm
++        steps:
++            - uses: actions/checkout@34e114876b0b11c390a56381ad16ebd13914f8d5 # v4.3.1
++              with:
++                fetch-depth: 0
++                fetch-tags: true
++            - name: make integration-dind
++              run: |
++                  docker logout
++                  rm -rf ~/.docker
++                  make integration-dind
diff --git a/tests/containers/python_docker.pm b/tests/containers/python_docker.pm
index b158420d59a5..bd7336efdb68 100644
--- a/tests/containers/python_docker.pm
+++ b/tests/containers/python_docker.pm
@@ -13,7 +13,6 @@ use serial_terminal qw(select_serial_terminal);
 use version_utils;
 use version;
 use utils;
-use Utils::Architectures qw(is_x86_64);
 use containers::bats;
 
 my $api_version;
@@ -58,8 +57,6 @@ sub test ($target) {
         "tests/integration/api_swarm_test.py",
         "tests/integration/models_swarm_test.py"
     );
-    # This test uses the vieux/sshfs plugin which doesn't seem to be available for other arches
-    push @ignore, "tests/integration/api_plugin_test.py" unless is_x86_64;
     my $ignore = join " ", map { "--ignore=$_" } @ignore;
 
     # Used by pytest to ignore individual tests