diff --git a/src/js/internal/quic/quic.ts b/src/js/internal/quic/quic.ts
index dc474e25e4f3..eac7ab58868a 100644
--- a/src/js/internal/quic/quic.ts
+++ b/src/js/internal/quic/quic.ts
@@ -2609,7 +2609,18 @@ class QuicStream {
     const inner = this.#inner;
 
     if (inner.pendingTrailers) {
-      this.sendTrailers(inner.pendingTrailers);
+      // Node v26.10.0: https://github.com/nodejs/node/blob/v26.10.0/lib/internal/quic/quic.js#L2794-L2807
+      let sent;
+      try {
+        sent = this.sendTrailers(inner.pendingTrailers);
+      } catch (error) {
+        this.destroy(error);
+        return;
+      }
+      if (!sent) {
+        this.destroy(ERR_QUIC_STREAM_ABORTED("Failed to submit trailing headers"));
+        return;
+      }
       inner.pendingTrailers = undefined;
     } else {
       const { onwanttrailers } = inner;
diff --git a/test/js/node/quic/quic-stream.test.ts b/test/js/node/quic/quic-stream.test.ts
index fe3a7b08b396..eb1946dc857c 100644
--- a/test/js/node/quic/quic-stream.test.ts
+++ b/test/js/node/quic/quic-stream.test.ts
@@ -284,6 +284,145 @@ describe("HTTP/3 header blocks that follow another header block", () => {
   });
 });
 
+// A stream sends `pendingTrailers` itself when the body is out, so the caller
+// has no answer to read. Node v26.10.0 destroys the stream when the block
+// cannot be sent (nodejs/node#65863).
+describe("pendingTrailers", () => {
+  const encoder = new TextEncoder();
+  const request = { ":method": "POST", ":scheme": "https", ":authority": "localhost" };
+  // Longer than a test: an idle timeout must not be what ends the session.
+  const transportParams = { maxIdleTimeout: 60 };
+
+  // One response with a body and `trailers` as its pendingTrailers. Gives how
+  // `closed` settles for the server stream, and what the client gets.
+  async function respondWith(trailers: Record<string, string>) {
+    let closed = "open";
+    const settled = Promise.withResolvers<string>();
+    const settle = (how: string) => {
+      closed = how;
+      settled.resolve(how);
+    };
+    const server = await listen(
+      async serverSession => {
+        serverSession.onstream = (stream: any) => {
+          stream.closed.catch(() => {});
+        };
+        await serverSession.closed.catch(() => {});
+      },
+      {
+        sni: { "*": { keys: [key], certs: [cert] } },
+        transportParams,
+        onheaders(this: any, headers: Record<string, any>) {
+          if (headers[":path"] !== "/trailers") {
+            this.sendHeaders({ ":status": "200" }, { terminal: true });
+            return;
+          }
+          this.closed.then(
+            () => settle("resolved"),
+            (err: any) => settle(err.code),
+          );
+          this.sendHeaders({ ":status": "200" });
+          this.pendingTrailers = trailers;
+          this.writer.writeSync(encoder.encode("body"));
+          this.writer.endSync();
+        },
+        // A stream is asked for its trailers only when this is set.
+        onwanttrailers() {},
+      },
+    );
+    let client: any;
+    // Not a graceful close. That waits for every stream, and a stream stays
+    // open when its trailers are never sent.
+    const dispose = async () => {
+      client?.destroy();
+      await server.destroy();
+    };
+    try {
+      client = await connect(server.address!, {
+        servername: "localhost",
+        verifyPeer: "manual",
+        transportParams,
+      } as SessionOptions);
+      await client.opened;
+
+      const clientTrailers = Promise.withResolvers<Record<string, string>>();
+      const stream = await client.createBidirectionalStream({
+        headers: { ...request, ":path": "/trailers" },
+        onheaders() {},
+        ontrailers: clientTrailers.resolve,
+      });
+      // A stream gets its trailers before it closes.
+      stream.closed.then(
+        () => clientTrailers.reject(new Error("the stream closed with no trailers")),
+        clientTrailers.reject,
+      );
+      clientTrailers.promise.catch(() => {});
+      const arrived = Promise.withResolvers<void>();
+      const body = (async () => {
+        let text = "";
+        try {
+          for await (const batch of stream) {
+            for (const chunk of batch) text += Buffer.from(chunk).toString("latin1");
+            if (text === "body") arrived.resolve();
+          }
+          return text;
+        } finally {
+          arrived.resolve();
+        }
+      })();
+      body.catch(() => {});
+      await arrived.promise;
+
+      // The server asks the stream for its trailers when the body leaves, which
+      // is before it gets this request. So the answer comes after that.
+      const answered = Promise.withResolvers<void>();
+      const later = await client.createBidirectionalStream({
+        headers: { ...request, ":path": "/" },
+        onheaders() {
+          answered.resolve();
+        },
+      });
+      later.closed.then(() => answered.reject(new Error("the stream closed with no answer")), answered.reject);
+      await answered.promise;
+      return {
+        closed,
+        settled: settled.promise,
+        body,
+        trailers: clientTrailers.promise,
+        [Symbol.asyncDispose]: dispose,
+      };
+    } catch (err) {
+      await dispose();
+      throw err;
+    }
+  }
+
+  test("a block that is sent reaches the client, and the stream closes with no error", async () => {
+    await using response = await respondWith({ "x-checksum": "abc123" });
+    expect({
+      trailers: { ...(await response.trailers) },
+      body: await response.body,
+      closed: await response.settled,
+    }).toEqual({ trailers: { "x-checksum": "abc123" }, body: "body", closed: "resolved" });
+  });
+
+  test("a block that sendTrailers() throws for destroys the stream with the error", async () => {
+    await using response = await respondWith({ connection: "close" });
+    expect(response.closed).toBe("ERR_HTTP2_INVALID_CONNECTION_HEADERS");
+    // destroy() still ends a response that the stream wrote and ended.
+    expect(await response.body).toBe("body");
+  });
+
+  test("a block that sendTrailers() answers false for destroys the stream", async () => {
+    // Latin-1 on the wire makes a NUL of U+0100. The block then has more
+    // pairs than it declares, and the native side refuses it.
+    await using response = await respondWith({ "x-bad": "a\u0100b" });
+    expect(response.closed).toBe("ERR_QUIC_STREAM_ABORTED");
+    // The client's read ends. The native side decides how.
+    await response.body.catch(() => {});
+  });
+});
+
 describe("verifyClient", () => {
   test("a server requiring a client certificate never surfaces streams from a client that presented none", async () => {
     let announcedStreams = 0;