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docs: shuffling page gives the measured aligner memory effect (#870) - #873
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Co-Authored-By: Claude <noreply@anthropic.com>
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Follow-up to #871. The page said in general terms that read order affects aligners. It now gives the measured effect from #870: bwa-mem2 peaked at 166 GB on the 21x CHM13 simulation as written and at 90 GB on the same reads shuffled (jobs 23383724 and 23394381), with flagstat agreeing to within 164 properly paired reads of 513M. The advice is now to shuffle before aligning a large genome.
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